Nurul Atifah, M.A. and Loo, H.K.C. and Wong, E.H. and Subramaniam, G. and Ho, S.E. and Selvi, P. and Parasakthi, N. and Kamarulzaman, A. (2005) Faecal prevalence of extended-spectrum ß-lactamase (ESBL)-producing coliforms in a geriatric population and among haematology patients. Malaysian Journal of Pathology, 27 (2). pp. 75-81. ISSN 0126-8635, DOI http://myais.fsktm.um.edu.my/1806/1/01Faecal.pdf.
|
PDF
1.pdf - Published Version Download (553kB) |
Abstract
Antimicrobial resistance to the extended-spectrum cephalosporins is increasingly reported worldwide. In the local setting, nosocomial infections with multi-resistant Gram-negative bacilli are not uncommon and are a growing concern. However, there is limited data on the carriage rates of such organisms in the local setting. In May 2001, a prospective study was carried out to determine the enteric carriage rates of ceftazidime-resistant Gram negative bacilli (CAZ-R GNB) among residents of nursing homes and from in-patients of the geriatric and adult haematology wards of University Malaya Medical Centre. Ceftazidime-resistant Gram-negative bacilli (CAZ-R GNB) were detected in 25 samples (30%), out of which 6 were from nursing home residents, 5 from geriatric in-patients and 14 from the haematology unit. A total of 28 CAZ-R GNB were isolated and Escherichia coli (10) and Klebsiella pneumoniae (7) were the predominant organisms. Resistance to ceftazidime in E. coli and Klebsiella was mediated by extended-spectrum beta-lactamases (ESBLs). Although the majority of the CAZ-R GNB were from patients in the haematology ward, the six nursing home residents with CAZ-R GNB were enteric carriers of ESBL-producing coliforms. Prior exposure to antibiotics was associated with carriage of ESBL organisms and to a lesser extent, the presence of urinary catheters.
Item Type: | Article |
---|---|
Funders: | UNSPECIFIED |
Additional Information: | University of Malaya, Faculty of Medicine, Dept. of Medical Microbiology |
Uncontrolled Keywords: | ESBL; Geriatric Population; Gram Negative Bacilli |
Subjects: | R Medicine |
Divisions: | Faculty of Medicine |
Depositing User: | Mr. Faizal Hamzah |
Date Deposited: | 09 Aug 2011 00:54 |
Last Modified: | 20 Oct 2014 04:05 |
URI: | http://eprints.um.edu.my/id/eprint/1960 |
Actions (login required)
View Item |