Transcriptomic evaluation of plant growth inhibitory activity of goniothalamin from the Malaysian medicinal plant goniothalamus andersonii

Wasano, Naoya and Takemura, Tomoko and Ismil, Raihan and Bakar, Baki and Fujii, Yoshiharu (2015) Transcriptomic evaluation of plant growth inhibitory activity of goniothalamin from the Malaysian medicinal plant goniothalamus andersonii. Natural Product Communications, 10 (5). pp. 725-727. ISSN 1934-578X

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Official URL: https://doi.org/10.1177/1934578X1501000507

Abstract

Goniothalamin produced by the Malaysian medicinal plant, Goniothalamus andersonii J. Sinclair, strongly inhibits plant growth. However, its mode of action has not been characterized at the gene expression level. We conducted DNA microarray assay to analyze the changes in early gene responses of Arabidopsis thaliana seedlings. After a 6-h exposure to goniothalamin, we observed an upregulation of genes highly associated with heat response, and 22 heat shock protein (AtHSP) genes were upregulated more than 50 fold. Together with these genes, we observed upregulation of the genes related to oxidative stress and protein folding. Also, the genes related to cell wall modification and cell growth, expansin (AtEXPA) genes, were significantly downregulated. The results suggested that goniothalamin induces oxidative stresses and inhibits the expression of cell wall-associated proteins resulting in growth inhibition of Arabidopsis seedlings.

Item Type: Article
Uncontrolled Keywords: DNA microarray; Expansins; Goniothalamin; Heat shock proteins; Plant growth inhibitory; Transcriptome; Unsaturated carbonyl groups
Subjects: Q Science > Q Science (General)
Q Science > QH Natural history
Divisions: Faculty of Science > Institute of Biological Sciences
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 28 Sep 2018 07:46
Last Modified: 29 Jan 2020 02:12
URI: http://eprints.um.edu.my/id/eprint/19470

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