(+)-Kunstlerone, a New Antioxidant Neolignan from the Leaves of Beilschmiedia kunstleri Gamble

Mollataghi, A. and Hadi, A.H. and Awang, K. and Mohamad, J. and Litaudon, M. and Mukhtar, M.R. (2011) (+)-Kunstlerone, a New Antioxidant Neolignan from the Leaves of Beilschmiedia kunstleri Gamble. Molecules. ISSN 1420-3049, DOI 21818061.

Full text not available from this repository.
Official URL: http://www.ncbi.nlm.nih.gov/pubmed/21818061

Abstract

A new neolignan, 3,4-dimethoxy-3',4'-methylenedioxy-2,9-epoxy-6,7-cyclo-1,8-neolign-11-en-5(5H)-one, which has been named (+)-kunstlerone (1), together with six known alkaloids: (+)-norboldine (2), (+)-N-methylisococlaurine (3), (+)-cassythicine (4), (+)-laurotetanine (5), (+)-boldine (6) and (-)-pallidine (7), were isolated from the leaves of Beilschmiedia kunstleri. The structures were established through various spectroscopic methods notably 1D- and 2D-NMR, UV, IR and LCMS-IT-TOF. (+)- Kunstlerone (1) showed a strong antioxidant activity, with an SC(50) of 20.0 µg/mL.

Item Type: Article
Funders: UNSPECIFIED
Additional Information: Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
Uncontrolled Keywords: Chemistry
Subjects: Q Science > QD Chemistry
R Medicine
Divisions: Faculty of Science > Department of Chemistry
Depositing User: Mr. Faizal Hamzah
Date Deposited: 08 Aug 2011 01:06
Last Modified: 26 Dec 2014 06:42
URI: http://eprints.um.edu.my/id/eprint/1947

Actions (login required)

View Item View Item