(+)-Kunstlerone, a New Antioxidant Neolignan from the Leaves of Beilschmiedia kunstleri Gamble.

Mollataghi , A.; Hadi , A.H.; Awang , K.; Mohamad , J.; Litaudon , M.; Mukhtar , M.R. (2011) (+)-Kunstlerone, a New Antioxidant Neolignan from the Leaves of Beilschmiedia kunstleri Gamble. Molecules. ISSN 1420-3049

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Abstract

A new neolignan, 3,4-dimethoxy-3',4'-methylenedioxy-2,9-epoxy-6,7-cyclo-1,8-neolign-11-en-5(5H)-one, which has been named (+)-kunstlerone (1), together with six known alkaloids: (+)-norboldine (2), (+)-N-methylisococlaurine (3), (+)-cassythicine (4), (+)-laurotetanine (5), (+)-boldine (6) and (-)-pallidine (7), were isolated from the leaves of Beilschmiedia kunstleri. The structures were established through various spectroscopic methods notably 1D- and 2D-NMR, UV, IR and LCMS-IT-TOF. (+)- Kunstlerone (1) showed a strong antioxidant activity, with an SC(50) of 20.0 µg/mL.

Item Type: Article
Creators:
  1. Mollataghi , A.(University of Malaya)
  2. Hadi , A.H.
  3. Awang , K.
  4. Mohamad , J.
  5. Litaudon , M.
  6. Mukhtar , M.R.
Journal or Publication Title: Molecules
Additional Information: Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
Uncontrolled Keywords: Chemistry
Subjects: Q Science > QD Chemistry
R Medicine
Divisions: Faculty of Science > Dept of Chemistry
Depositing User: Mr. Faizal Hamzah
Date Deposited: 08 Aug 2011 09:06
Last Modified: 08 Aug 2011 09:06
URI: http://eprints.um.edu.my/id/eprint/1947

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