Comparative analysis of essential oil composition of iranian and indian nigella sativa L. Extracted using supercritical fluid extraction and solvent extraction

Ghahramanloo, K.H. and Kamalidehghan, B. and Akbari Javar, H. and Teguh Widodo, R. and Majidzadeh, K. and Noordin, M.I. (2017) Comparative analysis of essential oil composition of iranian and indian nigella sativa L. Extracted using supercritical fluid extraction and solvent extraction. Drug Design, Development and Therapy, 11. pp. 2221-2226. ISSN 1177-8881

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Official URL: http://dx.doi.org/10.2147/DDDT.S87251

Abstract

The objective of this study was to compare the oil extraction yield and essential oil composition of Indian and Iranian Nigella sativa L. extracted by using Supercritical Fluid Extraction (SFE) and solvent extraction methods. In this study, a gas chromatography equipped with a mass spectrophotometer detector was employed for qualitative analysis of the essential oil composition of Indian and Iranian N. sativa L. The results indicated that the main fatty acid composition identified in the essential oils extracted by using SFE and solvent extraction were linoleic acid (22.4%–61.85%) and oleic acid (1.64%–18.97%). Thymoquinone (0.72%–21.03%) was found to be the major volatile compound in the extracted N. sativa oil. It was observed that the oil extraction efficiency obtained from SFE was significantly (P<0.05) higher than that achieved by the solvent extraction technique. The present study showed that SFE can be used as a more efficient technique for extraction of N. Sativa L. essential oil, which is composed of higher linoleic acid and thymoquinone contents compared to the essential oil obtained by the solvent extraction technique.

Item Type: Article
Uncontrolled Keywords: Nigella sativa L.; Essential oil extraction; Supercritical fluid extraction; Solvent extraction; Fatty acid composition; Thymoquinone; Linoleic acid
Subjects: R Medicine
R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 12 Sep 2018 01:19
Last Modified: 12 Sep 2018 01:19
URI: http://eprints.um.edu.my/id/eprint/19183

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