Remarkable bone formation following gefitinib for extensive lytic bone metastasis: A report of two cases

Bashir, E.S. and Kwan, A.K.N. and Chan, C.Y.W. and Kwan, M.K. (2016) Remarkable bone formation following gefitinib for extensive lytic bone metastasis: A report of two cases. Journal of Orthopaedic Surgery, 24 (3). pp. 421-423. ISSN 1022-5536

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Official URL: http://journals.sagepub.com/doi/10.1177/1602400330

Abstract

Gefitinib inhibits the epidermal growth factor receptor tyrosine kinase and improves survival in patients with non-small-cell lung cancer. We report 2 patients with extensive lytic bony metastasis in the spine and pelvis secondary to advanced pulmonary adenocarcinoma who were treated with gefitinib and had remarkable bone formation in the lytic bone lesions in the spine and pelvis. Surgery for stabilisation was avoided.

Item Type: Article
Uncontrolled Keywords: Adenocarcinoma of lung; Bone cysts; Gefitinib; Neoplasm metastasis; Receptor; Epidermal growth factor
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 07 Dec 2017 03:11
Last Modified: 07 Dec 2017 03:11
URI: http://eprints.um.edu.my/id/eprint/18476

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