Spectroscopic (UV/VIS, Raman) and Electrophoresis Study of Cytosine-Guanine Oligonucleotide DNA Influenced by Magnetic Field

Banihashemian, S.M. and Periasamy, V. and Goh, B.T. and Rahman, S.A. (2016) Spectroscopic (UV/VIS, Raman) and Electrophoresis Study of Cytosine-Guanine Oligonucleotide DNA Influenced by Magnetic Field. PLoS ONE, 11 (3). 0149488. ISSN 1932-6203

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Official URL: https://doi.org/10.1371/journal.pone.0149488

Abstract

Studying the effect of a magnetic field on oligonucleotide DNA can provide a novel DNA manipulation technique for potential application in bioengineering and medicine. In this work, the optical and electrochemical response of a 100 bases oligonucleotides DNA, cytosine- guanine (CG100), is investigated via exposure to different magnetic fields (250, 500, 750, and 1000 mT). As a result of the optical response of CG100 to the magnetic field, the ultra-violet-visible spectrum indicated a slight variation in the band gap of CG100 of about 0.3 eV. Raman spectroscopy showed a significant deviation in hydrogen and phosphate bonds' vibration after exposure to the magnetic field. Oligonucleotide DNA mobility was investigated in the external electric field using the gel electrophoresis technique, which revealed a small decrease in the migration of CG100 after exposure to the magnetic field.

Item Type: Article
Uncontrolled Keywords: DNA; Electrophoresis; Magnetics; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman
Subjects: Q Science > Q Science (General)
Q Science > QC Physics
Divisions: Faculty of Science > Dept of Physics
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 07 Dec 2017 01:25
Last Modified: 07 Dec 2017 01:25
URI: http://eprints.um.edu.my/id/eprint/18460

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