Banihashemian, S.M. and Periasamy, V. and Goh, B.T. and Rahman, S.A. (2016) Spectroscopic (UV/VIS, Raman) and Electrophoresis Study of Cytosine-Guanine Oligonucleotide DNA Influenced by Magnetic Field. PLoS ONE, 11 (3). 0149488. ISSN 1932-6203, DOI https://doi.org/10.1371/journal.pone.0149488.
Full text not available from this repository.Abstract
Studying the effect of a magnetic field on oligonucleotide DNA can provide a novel DNA manipulation technique for potential application in bioengineering and medicine. In this work, the optical and electrochemical response of a 100 bases oligonucleotides DNA, cytosine- guanine (CG100), is investigated via exposure to different magnetic fields (250, 500, 750, and 1000 mT). As a result of the optical response of CG100 to the magnetic field, the ultra-violet-visible spectrum indicated a slight variation in the band gap of CG100 of about 0.3 eV. Raman spectroscopy showed a significant deviation in hydrogen and phosphate bonds' vibration after exposure to the magnetic field. Oligonucleotide DNA mobility was investigated in the external electric field using the gel electrophoresis technique, which revealed a small decrease in the migration of CG100 after exposure to the magnetic field.
| Item Type: | Article |
|---|---|
| Funders: | PPP-BKP grant BK003-2015, UM/MOHE High Impact Research Grant allocation of F000006-21001, HIR grants (J-21002-73823 and UM.C/HIR/MOHE/SC/06), FRGS grant (FP004/2013A) |
| Uncontrolled Keywords: | DNA; Electrophoresis; Magnetics; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman |
| Subjects: | Q Science > Q Science (General) Q Science > QC Physics |
| Divisions: | Faculty of Science > Department of Physics |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 07 Dec 2017 01:25 |
| Last Modified: | 07 Dec 2017 01:25 |
| URI: | http://eprints.um.edu.my/id/eprint/18460 |
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