Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia

Benacer, D. and Mohd Zain, S.N. and Ooi, P.T. and Thong, Kwai Lin (2017) Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia. Indian Journal of Medical Microbiology, 35 (1). pp. 124-128. ISSN 0255-0857

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Abstract

Leptospirosis is a zoonosis with worldwide distribution caused by pathogenic spirochetes of the genus Leptospira. The aim of this study was to evaluate the susceptibility of isolates obtained from different hosts. A total of 65 Leptospira isolates from humans (n = 1), zoonoses (rat, n = 60; dog, n = 1; swine, n = 1) and environment (n = 2) were tested against six antibiotics. All the isolates were resistant to trimethoprim and sulphamethoxazole and had high MIC toward chloramphenicol (MIC90: 6.25 μg/ml). All except one environment isolate were sensitive to ampicillin, doxycycline and penicillin G.

Item Type: Article
Uncontrolled Keywords: Antimicrobial susceptibility; Leptospira; Leptospirosis; Minimal inhibitory concentration
Subjects: Q Science > Q Science (General)
Q Science > QH Natural history
R Medicine
Divisions: Faculty of Science > Institute of Biological Sciences
Depositing User: Prof. Dr Kwai Lin Thong
Date Deposited: 30 Nov 2017 01:55
Last Modified: 15 Oct 2018 05:35
URI: http://eprints.um.edu.my/id/eprint/18382

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