Prevalence and risk factors for asymptomatic intestinal microsporidiosis among aboriginal school children in Pahang, Malaysia

Anuar, T.S. and Bakar, N.H.A. and Al-Mekhlafi, Hesham Mahyoub and Moktar, N. and Osman, E. (2016) Prevalence and risk factors for asymptomatic intestinal microsporidiosis among aboriginal school children in Pahang, Malaysia. The Southeast Asian Journal of Tropical Medicine and Public Health, 47 (3). pp. 441-449. ISSN 0125-1562, DOI PubMed ID: 27405127.

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Official URL: http://www.tm.mahidol.ac.th/seameo/2016-47-3/11-66...

Abstract

The epidemiology and environmental factors affecting transmission of human microsporidiosis are poorly understood. We conducted the present study to determine the prevalence and risk factors associated with asymptomatic intestinal microsporidiosis among aboriginal school children in the Kuala Krau District, Pahang State, Malaysia. We collected stool samples from 255 school children and examined the samples using Gram-chromotrope Kinyoun stain. We also collected demographic, socioeconomic, environmental and personal hygiene information using a pre-tested questionnaire. Sixty-nine of the children was positive for microsporidia: 72.5% and 27.5% were low (1+) and moderate (2+) excretions of microsporidia spores, respectively. Univariate and multivariate analyses showed being aged ≥10 years (p = 0.026), using an unsafe water supply as a source for drinking water (p = 0.044) and having close contact with domestic animals (p = 0.031) were all significantly associated with microsporidial infection among study subjects. Our findings suggest asymptomatic intestinal microsporidiosis is common in the study population, more than previously reported. In the study population, control measures need to be implemented, such as good personal hygiene, proper sanitation and safe drinking water supply.

Item Type: Article
Funders: Universiti Teknologi MARA and Ministry of Education Malaysia: Research Acculturation Grant Scheme (600-RMI/RAGS 5/3 [52/2014]), Universiti Kebangsaan Malaysia: UKMMC Fundamental Research Grant [FF-165-2011]
Uncontrolled Keywords: Microsporidia; Epidemiology; Asymptomatic; Children; Malaysia
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 17 Nov 2017 08:26
Last Modified: 12 Apr 2021 03:55
URI: http://eprints.um.edu.my/id/eprint/18319

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