Genetic variants of Orientia tsutsugamushi identified from scrub typhus cases in Malaysia

Zan, H.A.M. and Ponnampalavanar, S. and Omar, S.F.S. and Savithiri, P.D. and Lim, Y.A.L. and Tay, S.T. (2016) Genetic variants of Orientia tsutsugamushi identified from scrub typhus cases in Malaysia. Tropical Biomedicine, 33 (1). pp. 203-208. ISSN 0127-5720

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Abstract

We report herein the clinical presentation and diagnosis of scrub typhus in three patients attending a teaching hospital in Malaysia. Three genetic variants belonged to the Karp and Gilliam strains of O. tsutsugamushi were amplified from the acute blood samples of the patients by a nested polymerase chain reaction assay. The circulation of different genetic variants of O. tsutsugamushi strains might complicate the presentation and severity of scrub typhus. Loop-PCR is a promising diagnostic tool for rapid diagnosis of scrub typhus.

Item Type: Article
Uncontrolled Keywords: Genetic variants; Orientia tsutsugamushi; Scrub typhus cases; Malaysia
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 17 Nov 2017 07:38
Last Modified: 17 Nov 2017 07:38
URI: http://eprints.um.edu.my/id/eprint/18313

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