Cardiovascular risk scores do not account for the effect of treatment: a review.

Liew, S.M.; Doust, J.; Glasziou, P. (2011) Cardiovascular risk scores do not account for the effect of treatment: a review. Heart (British Cardiac Society), 97 (9). pp. 689-97. ISSN 1468-201X

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Abstract

The use of risk-factor-modifying drugs-for example, statins-and disease-modifying medication-for example, platelet inhibitors-was not accounted for. In addition, none of the risk scores addressed the effect of treatment drop-ins-that is, treatment started during the study period. Ideally, a risk score should be derived from a population free from treatment. The lack of accounting for treatment effect and the wide variation in study characteristics, predictors and outcomes causes difficulties in the use of cardiovascular risk scores for clinical treatment decision.

Item Type: Article
Creators:
  1. Liew, S.M.
  2. Doust, J.
  3. Glasziou, P.
Journal or Publication Title: Heart (British Cardiac Society)
Additional Information: Department of Primary Care Medicine and Julius Center UM,University of Malaya, KualaLumpur, Malaysia.
Uncontrolled Keywords: Adult; Aged; Cardiovascular Agents/therapeutic use
Subjects: R Medicine
Divisions: UNSPECIFIED
Depositing User: Mr. Faizal Hamzah
Date Deposited: 23 Jul 2011 09:43
Last Modified: 23 Jul 2011 09:43
URI: http://eprints.um.edu.my/id/eprint/1826

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