Maluin, F.N. and Mohamad, S. and Rattanarat, P. and Siangproh, W. and Chailapakul, O. and Issam, A.M. and Manan, N.S.A. (2016) Synthesis of PANI/hematite/PB hybrid nanocomposites and fabrication as screen printed paper based sensors for cholesterol detection. Analytical Methods, 8 (45). pp. 8049-8058. ISSN 1759-9660, DOI https://doi.org/10.1039/C6AY02478E.
Full text not available from this repository.Abstract
In this work, the composites of polyaniline/nano-hematite (α-Fe2O3)/Prussian Blue (PB) were successfully synthesized via a sonochemical method. This nanocomposite (PB/CPANI) has been used for the modification of paper-based sensors for cholesterol detection. The electrochemical studies of this nanocomposite showed a well-defined cyclic voltammogram for hydrogen peroxide (H2O2) with a remarkable electrochemical sensitivity. This nanocomposite modified paper-based electrode also showed excellent electrocatalytic activity towards H2O2 in the interference-free cathodic region. In addition, cholesterol oxidase was immobilized on the PB/CPANI-modified paper-based electrode for selective detection of cholesterol. Under optimum conditions, a linear range of 0.6–6.0 mM with a very low detection limit of 0.52 mM for cholesterol and a good sensitivity of 411.7 μA mM−1 cm−2 were obtained which indicated that the method presented is outstandingly appropriate to determine cholesterol in bovine serum albumin. This work might be an alternative, interference-free, and cost-effective approach for biomonitoring of cholesterol both in methodological studies and in clinical laboratories.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Body fluids; Chemical detection; Cost effectiveness; Electrodes; Nanocomposites; Paper; Polyaniline; Sonochemistry |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science > Department of Chemistry |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 24 Aug 2017 09:23 |
| Last Modified: | 24 Aug 2017 09:23 |
| URI: | http://eprints.um.edu.my/id/eprint/17716 |
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