Anti-Inflammatory Activity of Calophyllum inophyllum Fruits Extracts

Ilham, Zul (2014) Anti-Inflammatory Activity of Calophyllum inophyllum Fruits Extracts. Procedia Chemistry, 13. pp. 218-220. ISSN 1876-6196,

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Abstract

In the present work, we are reporting the isolation. characterisation and bioactvity of inophyllums, xanthones and other compounds found in the fruits of Callophyllum inophyllum. In-vitro assays demonstrated that the crude extract at concentration of 50 Pg/ml inhibited 77% and 88% cyclooxygenase and lipooxygenase activities, respectively, indicating its potential as antiinflamatory agent. Phytochemical studies was also conducted on the fruits. Inophyllum A, inophyllum C, inophyllum E, calophylloide, calophynic acid, 11,12-anhydroinophyllum A, 1,7-dihydroxy-6-methoxyxanthone, potocatechuic acid, gallic acid, n-nonacosane, E-sitosterol and sitosterol-3-O-E-D-glucopyranoside were isolated and idetified. On the HPLC chromatogram, at least 18 compounds can be detected.

Item Type:	Article
Funders:	UNSPECIFIED
Uncontrolled Keywords:	Calophyllum inophyllum; Antiinflammatory; Xanthone; Isoprenylated coumarin, Sitosterol
Subjects:	Q Science > QD Chemistry Q Science > QH Natural history > QH301 Biology T Technology > TP Chemical technology
Divisions:	Faculty of Science > Institute of Biological Sciences
Depositing User:	Dr. Zul Ilham
Date Deposited:	05 Dec 2016 10:40
Last Modified:	30 Mar 2021 02:25
URI:	http://eprints.um.edu.my/id/eprint/16777

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