Anti-Inflammatory Activity of Calophyllum inophyllum Fruits Extracts

Ilham, Zul (2014) Anti-Inflammatory Activity of Calophyllum inophyllum Fruits Extracts. Procedia Chemistry, 13. pp. 218-220. ISSN 1876-6196

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Official URL: http://dx.doi.org/10.1016/j.proche.2014.12.031

Abstract

In the present work, we are reporting the isolation. characterisation and bioactvity of inophyllums, xanthones and other compounds found in the fruits of Callophyllum inophyllum. In-vitro assays demonstrated that the crude extract at concentration of 50 Pg/ml inhibited 77% and 88% cyclooxygenase and lipooxygenase activities, respectively, indicating its potential as antiinflamatory agent. Phytochemical studies was also conducted on the fruits. Inophyllum A, inophyllum C, inophyllum E, calophylloide, calophynic acid, 11,12-anhydroinophyllum A, 1,7-dihydroxy-6-methoxyxanthone, potocatechuic acid, gallic acid, n-nonacosane, E-sitosterol and sitosterol-3-O-E-D-glucopyranoside were isolated and idetified. On the HPLC chromatogram, at least 18 compounds can be detected.

Item Type: Article
Uncontrolled Keywords: Calophyllum inophyllum; Antiinflammatory; Xanthone; Isoprenylated coumarin, Sitosterol
Subjects: Q Science > QD Chemistry
Q Science > QH Natural history > QH301 Biology
T Technology > TP Chemical technology
Divisions: Faculty of Science > Institute of Biological Sciences
Depositing User: Dr. Zul Ilham
Date Deposited: 05 Dec 2016 10:40
Last Modified: 30 Mar 2021 02:25
URI: http://eprints.um.edu.my/id/eprint/16777

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