Genome sequence of Streptomyces pluripotens MUSC 135(T) exhibiting antibacterial and antioxidant activity

Ser, Hooi Leng and Tan, Wen Si and Ab Mutalib, Nurul Syakima and Cheng, Huey Jia and Yin, Wai Fong and Chan, Kok Gan and Lee, Learn Han (2015) Genome sequence of Streptomyces pluripotens MUSC 135(T) exhibiting antibacterial and antioxidant activity. Marine Genomics, 24 (3). pp. 281-283. ISSN 1874-7787

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Official URL: https://doi.org/10.1016/j.margen.2015.09.010

Abstract

Isolated from intertidal soil, Streptomyces pluripotens MUSC 135(T) produces a broad-spectrum bacteriocin against the pathogens methicillin-resistant Staphylococcus aureus (MRSA) ATCC BAA-44(T), Salmonella typhi ATCC 19430(T) and Aeromonas hydrophila ATCC 7966(T). Along with antibacterial activity, fermentation studies on strain MUSC 135(T) revealed production of antioxidant(s). The high quality draft genome of MUSC 135(T) comprises 7,480,269 bp with G + C content of 70.00%. Through bioinformatics analysis, 72 gene clusters identified in the genome were associated with the production of secondary metabolites, which may shed light on the identity of these bioactive compounds. (c) 2015 Elsevier B.V. All rights reserved.

Item Type: Article
Uncontrolled Keywords: Streptomyces pluripotens; Methycillin-resistant Staphylococcus aureus; MRSA; Bacteriocin; Genome
Subjects: Q Science > QR Microbiology
Depositing User: Mrs. Siti Mawarni Salim
Date Deposited: 05 Sep 2016 01:13
Last Modified: 23 Dec 2019 05:51
URI: http://eprints.um.edu.my/id/eprint/16360

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