Bang, L.T. and Ramesh, Singh and Purbolaksono, Judha and Ching, Yern Chee and Long, B.D. and Chandran, Hari and Ramesh, Subramaniam and Othman, R. (2015) Effects of silicate and carbonate substitution on the properties of hydroxyapatite prepared by aqueous co-precipitation method. Materials & Design, 87. pp. 788-796. ISSN 0261-3069, DOI https://doi.org/10.1016/j.matdes.2015.08.069.
Full text not available from this repository.Abstract
This research was conducted to investigate the effects of silicate and carbonate substitutions in hydroxyapatite (HA) on phase retention, physical properties, and in vitro biological response. A wet chemical method was employed to synthesize silicate-substituted HA (Si-HA) and carbonate-substituted HA (CHA). It was shown that the presence of silicate and carbonate ions in the HA lattice increases the specific surface area and Ca/P molar ratio. In addition, the substitution also resulted in a reduction in the crystallinity of the HA powder and promoted better bioactivity of the sintered body. This was confirmed through in vitro cell culture experiment which revealed that the osteoblast cells adhered well on the surface of the ceramic and that ionic-substituted HA exhibited better cell performance than the control HA. (C) 2015 Elsevier Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Hydroxyapatite; Ionic-substituted hydroxyapatite; Characterization; In vitro evaluation; Cell response |
| Subjects: | Q Science > Q Science (General) |
| Divisions: | Faculty of Engineering Faculty of Medicine Faculty of Science > Department of Physics |
| Depositing User: | Mrs. Siti Mawarni Salim |
| Date Deposited: | 04 Aug 2016 05:15 |
| Last Modified: | 05 Dec 2019 06:21 |
| URI: | http://eprints.um.edu.my/id/eprint/16185 |
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