Gong, P. and Chin, L. and Es'haghian, S. and Liew, Y.M. and Wood, F.M. and Sampson, D.D. and McLaughlin, R.A. (2014) Imaging of skin birefringence for human scar assessment using polarization-sensitive optical coherence tomography aided by vascular masking. Journal of Biomedical Optics (JBO), 19 (12).
Full text not available from this repository.Abstract
We demonstrate the in vivo assessment of human scars by parametric imaging of birefringence using polarization-sensitive optical coherence tomography (PS-OCT). Such in vivo assessment is subject to artifacts in the detected birefringence caused by scattering from blood vessels. To reduce these artifacts, we preprocessed the PS-OCT data using a vascular masking technique. The birefringence of the remaining tissue regions was then automatically quantified. Results from the scars and contralateral or adjacent normal skin of 13 patients show a correspondence of birefringence with scar type: the ratio of birefringence of hypertrophic scars to corresponding normal skin is 2.2 +/- 0.2 (mean +/- standard deviation), while the ratio of birefringence of normotrophic scars to normal skin is 1.1 +/- 0.4. This method represents a new clinically applicable means for objective, quantitative human scar assessment. (C) 2014 Society of Photo-Optical Instrumentation Engineers (SPIE)
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Polarization-sensitive optical coherence tomography; birefringence; collagen; hypertrophic scars; normotrophic scars; burn scars; speckle decorrelation; vessel detection; vascular masking; parametric imaging |
| Subjects: | R Medicine |
| Depositing User: | Dr Mohd Faizal Hamzah |
| Date Deposited: | 22 Jan 2016 01:56 |
| Last Modified: | 22 Jan 2016 01:56 |
| URI: | http://eprints.um.edu.my/id/eprint/15543 |
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