Sim, Yoke-Leng. and Khan, M.N. (2010) Kinetics and mechanism of tertiary amine-catalyzed cleavage of N `-morpholino-N-(2 `-methoxyphenyl)phthalamide: Kinetic evidence for the presence of a reactive intermediate on the reaction path. International Journal of Chemical Kinetics, 42 (5). pp. 263-272. ISSN 0538-8066,
Full text not available from this repository.Abstract
Pseudo-first-order rate constants (k(obs)) for tertiary amine (DABCO and Me(3)N) buffer-catalyzed cyclization of N'-morpholino-N-(2'-methoxyphenyl)phthalamide (1) to N-(2'-methoxyphenyl)phthalimide (2) reveal saturation (nonlinear) plots of k(obs) versus vertical bar Buf vertical bar(T) (total tertiary amine buffer concentration) at a constant pH. Such plots at different pH have been attributed to the presence of a reactive intermediate (T(-)) formed by tertiary amine buffer-catalyzed intramolecular nucleophilic addition of the secondary amide nitrogen to the carbonyl carbon of the tertiary amide group of 1. (C) 2010 Wiley Periodicals. Inc. Int J Chem Kinet 42: 263-272, 2010
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Subjects: | Q Science > QD Chemistry |
| Depositing User: | Dr Mohd Faizal Hamzah |
| Date Deposited: | 11 Nov 2015 01:48 |
| Last Modified: | 11 Nov 2015 01:48 |
| URI: | http://eprints.um.edu.my/id/eprint/14713 |
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