Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus

Razmavar, S. and Abdulla, M.A. and Ismail, S. and Hassandarvish, P. (2014) Antibacterial Activity of Leaf Extracts of Baeckea frutescens against Methicillin-Resistant Staphylococcus aureus. BioMed Research International, 2014. pp. 1-5. ISSN 2314-6133, DOI https://doi.org/10.1155/2014/521287.

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Official URL: http://www.hindawi.com/journals/bmri/2014/521287/

Abstract

This study was based on screening antibacterial activity of the ethanol extract of Baeckea frutescens L. against MRSA clinical isolates, analyzes the potential antibacterial compound, and assesses the cytotoxicity effect of the extract in tissue culture. Leaves of Baeckea frutescens L. were shade dried, powdered, and extracted using solvent ethanol. Preliminary phytochemical screening of the crude extracts revealed the presence of alkaloids, flavonoids, steroids, terpenoids, phenols, and carbohydrates. The presence of these bioactive constituents is related to the antibacterial activity of the plant. Disc diffusion method revealed a high degree of activity against microorganisms. The results confirm that Baeckea frutescens L. can be used as a source of drugs to fight infections caused by susceptible bacteria.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Antibacterial Activity; Leaf Extracts; Baeckea frutescens; Methicillin-Resistant; Staphylococcus aureus
Subjects: Q Science > Q Science (General)
Q Science > QH Natural history
Divisions: Faculty of Science
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 05 Nov 2015 09:13
Last Modified: 05 Nov 2015 09:13
URI: http://eprints.um.edu.my/id/eprint/14527

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