ABCB1 C3435T polymorphism and the risk of resistance to antiepileptic drugs in epilepsy: a systematic review and meta-analysis.

Haerian, B.S. and Roslan, H. and Raymond, A.A. and Tan, C.T. and Lim, K.S. and Zulkifli, S.Z. and Mohamed, E.H.M. and Tan, H.J. and Mohamed, Z. (2010) ABCB1 C3435T polymorphism and the risk of resistance to antiepileptic drugs in epilepsy: a systematic review and meta-analysis. Seizure : the journal of the British Epilepsy Association, 19 (6). pp. 339-46. ISSN 1532-2688

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Official URL: http://www.ncbi.nlm.nih.gov/pubmed/20605481

Abstract

We failed to show an association between the ABCB1 C3435T polymorphism and the risk of drug-resistance suggesting a revision in contribution of this polymorphism in the multi-drug transporters hypothesis of pharmacoresistance to AEDs in epilepsy.

Item Type: Article
Additional Information: Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. batoolsadat@yahoo.com
Uncontrolled Keywords: Anticonvulsants/therapeutic use; Data Interpretation, Statistical
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Medicine
Depositing User: Mr. Faizal Hamzah
Date Deposited: 25 May 2011 02:49
Last Modified: 11 Dec 2014 06:57
URI: http://eprints.um.edu.my/id/eprint/1343

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