ABCB1 C3435T polymorphism and the risk of resistance to antiepileptic drugs in epilepsy: a systematic review and meta-analysis.

Haerian, B.S.; Roslan, H.; Raymond, A.A.; Tan, C.T.; Lim, K.S.; Zulkifli, S.Z.; Mohamed, E.H.M.; Tan, H.J.; Mohamed, Z. (2010) ABCB1 C3435T polymorphism and the risk of resistance to antiepileptic drugs in epilepsy: a systematic review and meta-analysis. Seizure : the journal of the British Epilepsy Association, 19 (6). pp. 339-46. ISSN 1532-2688

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Abstract

We failed to show an association between the ABCB1 C3435T polymorphism and the risk of drug-resistance suggesting a revision in contribution of this polymorphism in the multi-drug transporters hypothesis of pharmacoresistance to AEDs in epilepsy.

Item Type: Article
Creators:
  1. Haerian, B.S.
  2. Roslan, H.
  3. Raymond, A.A.
  4. Tan, C.T.
  5. Lim, K.S.
  6. Zulkifli, S.Z.
  7. Mohamed, E.H.M.
  8. Tan, H.J.
  9. Mohamed, Z.
Journal or Publication Title: Seizure : the journal of the British Epilepsy Association
Additional Information: Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. batoolsadat@yahoo.com
Uncontrolled Keywords: Anticonvulsants/therapeutic use; Data Interpretation, Statistical
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Medicine
Depositing User: Mr. Faizal Hamzah
Date Deposited: 25 May 2011 10:49
Last Modified: 11 Dec 2014 14:57
URI: http://eprints.um.edu.my/id/eprint/1343

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