ABCB1 C3435T polymorphism and the risk of resistance to antiepileptic drugs in epilepsy: a systematic review and meta-analysis.

Haerian, B S; Roslan, H; Raymond, A A; Tan, C T; Lim, K S; Zulkifli, S Z; Mohamed, E H M; Tan, H J; Mohamed, Z (2010) ABCB1 C3435T polymorphism and the risk of resistance to antiepileptic drugs in epilepsy: a systematic review and meta-analysis. Seizure : the journal of the British Epilepsy Association, 19 (6). pp. 339-46. ISSN 1532-2688

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Abstract

We failed to show an association between the ABCB1 C3435T polymorphism and the risk of drug-resistance suggesting a revision in contribution of this polymorphism in the multi-drug transporters hypothesis of pharmacoresistance to AEDs in epilepsy.

Item Type: Article
Creators:
  1. Haerian, B S
  2. Roslan, H
  3. Raymond, A A
  4. Tan, C T
  5. Lim, K S
  6. Zulkifli, S Z
  7. Mohamed, E H M
  8. Tan, H J
  9. Mohamed, Z
Journal or Publication Title: Seizure : the journal of the British Epilepsy Association
Additional Information: Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. batoolsadat@yahoo.com
Uncontrolled Keywords: Anticonvulsants/therapeutic use; Data Interpretation, Statistical
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Medicine
Depositing User: Mr. Faizal Hamzah
Date Deposited: 25 May 2011 10:49
Last Modified: 25 May 2011 10:49
URI: http://eprints.um.edu.my/id/eprint/1343

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