Immunological diagnosis of human angiostrongyliasis due to Angiostrongylus cantonensis (Nematoda: Angiostrongylidae)

Eamsobhana, Praphathip and Yong, Hoi Sen (2009) Immunological diagnosis of human angiostrongyliasis due to Angiostrongylus cantonensis (Nematoda: Angiostrongylidae). International Journal of Infectious Diseases, 13 (4). pp. 425-431. ISSN 1201-9712

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Abstract

Angiostrongylus cantonensis-associated eosinophilic meningitis in humans has been commonly reported worldwide. However parasitologically confirmed cases are not common, as the parasite has been recovered only infrequently from the cerebrospinal fluid of patients. The potential value of immunodiagnosis is therefore self-evident. Immunological tests can also help in the differential diagnosis of parasitic (particularly helminths) infections that cause eosinophilic meningitis. This paper summarizes the state of and advances in the immunological diagnosis of human angiostrongyliasis due to Angiostrongylus (= Parastrongylus) cantonensis. A specific antigen is available for the definitive diagnosis and unequivocal differentiation of eosinophilic meningitis due to helminth infections. Rapid diagnostic kits based on dot-blot ELISA have been developed and have proved to be simple, effective, and economical for field use.

Item Type: Article
Uncontrolled Keywords: Angiostrongylus cantonensis; Parastrongylus cantonensis; Eosinophilic meningitis; Rapid diagnostic test; Immunoblot; Dot-blot ELISA
Subjects: Q Science > Q Science (General)
Q Science > QH Natural history
Divisions: Faculty of Science > Institute of Biological Sciences
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 27 Apr 2015 02:54
Last Modified: 05 Dec 2019 04:21
URI: http://eprints.um.edu.my/id/eprint/13392

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