Phyllanthus spp. induces selective growth inhibition of PC-3 and MeWo human cancer cells through modulation of cell cycle and induction of apoptosis.

Tang, Y.; Jaganath, I.B.; Sekaran, S.D. (2010) Phyllanthus spp. induces selective growth inhibition of PC-3 and MeWo human cancer cells through modulation of cell cycle and induction of apoptosis. PloS one, 5 (9). e12644. ISSN 1932-6203

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Abstract

Phyllanthus plant exerts its growth inhibition effect in a selective manner towards cancer cells through the modulation of cell cycle and induction of apoptosis via caspases activation in melanoma and prostate cancer cells. Hence, Phyllanthus may be sourced for the development of a potent apoptosis-inducing anticancer agent.

Item Type: Article
Creators:
  1. Tang, Y.
  2. Jaganath, I.B.
  3. Sekaran, S.D.
Journal or Publication Title: PloS one
Additional Information: Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Uncontrolled Keywords: Antineoplastic Agents, Phytogenic/pharmacology; Apoptosis/drug effects
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Mr. Faizal Hamzah
Date Deposited: 19 May 2011 10:38
Last Modified: 19 May 2011 10:38
URI: http://eprints.um.edu.my/id/eprint/1276

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