Establishing and managing a periodontal biobank for research: the sharing of experience

Vaithilingam, R.D. and Safii, S.H. and Baharuddin, N.A. and Karen-Ng, L.P. and Saub, R. and Ariffin, F. and Ramli, H. and Shariffudin, A. and Hidayat, M.F.H. and Raman, R. and Chan, Y.K. and Rani, N.A. and Rahim, R.A. and Shahrudidin, N. and Cheong, S.C. and Bartold, P.M. and Zain, R.B. (2015) Establishing and managing a periodontal biobank for research: the sharing of experience. Oral Diseases.

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Periodontal bio-repositories, which allow banking of clinically validated human data and biological samples, provide an opportunity to derive biomarkers for periodontal diagnosis, prognosis and therapeutic activities which are expected to improve patient management. This article presents the establishing of the Malaysian Periodontal Database and Biobank System (MPDBS) which was initiated in 2011 with the aim to facilitate periodontal research. Partnerships were established with collaborating centres. Policies on specimen access, authorship and acknowledgement policies were agreed upon by all participating centres before the initiation of the periodontal biobank. Ethical approval for the collection of samples and data were obtained from institutional ethics review boards. A broad-based approach for informed consent was used, which covered areas related to quality of life impacts, genetics and molecular aspects of periodontal disease. Sample collection and processing was performed using a standardized protocol. Biobanking resources such as equipment and freezers were shared with the Malaysian Oral Cancer Database and Tissue Bank System (MOCDTBS). In the development of the MPDBS, challenges that were previously faced by the MOCDTBS were considered. Future challenges in terms of ethical and legal issues will be faced when international collaborations necessitate the transportation of specimens across borders.

Item Type: Article
Subjects: R Medicine > RK Dentistry
Divisions: Faculty of Dentistry
Depositing User: Mr Ahmad Azwan Azman
Date Deposited: 09 Feb 2015 04:46
Last Modified: 09 Feb 2015 04:46

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