Nephrotic Syndrome in a Patient with Relapsed of Chronic Myeloid Leukemia after Peripheral Blood Stem Cell Transplantation

Bee, P.C.; Gan, G.G.; Sangkar, V.J.; Haris, A.R. (2008) Nephrotic Syndrome in a Patient with Relapsed of Chronic Myeloid Leukemia after Peripheral Blood Stem Cell Transplantation. Medical Journal of Malaysia, 63 (1). pp. 71-72. ISSN 0300-5283

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Abstract

Nephrotic syndrome (NS) is a well documented complication after allogeneic peripheral blood stem cell transplantation. It is usually due to autoimmune glomerulonephritis and thought to be a clinical manifestation of graft versus host disease. NS has also been reported to be associated with other hematological malignancies. We report a case of nephrotic syndrome in a patient who relapsed after allogeneic peripheral blood stem cell transplantation (PBSCT) for chronic myeloid leukemia (CML). The renal biopsy was suggestive of minimal change disease. There was no other evidence of graft versus host disease. He was treated with high dose prednisolone, with no response and finally succumbed to the underlying disease.

Item Type: Article
Creators:
  1. Bee, P.C.(Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, MALAYSIA)
  2. Gan, G.G.(Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, MALAYSIA)
  3. Sangkar, V.J.(Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, MALAYSIA)
  4. Haris, A.R.(Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, MALAYSIA)
Journal or Publication Title: Medical Journal of Malaysia
Uncontrolled Keywords: Nephrotic syndrome; GVHD; PBSCT; Chronic myeloid leukemia
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 14 Jan 2015 10:01
Last Modified: 14 Jan 2015 10:01
URI: http://eprints.um.edu.my/id/eprint/12021

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