A Case of T-Cell Acute Lymphoblastic Leukemia after Treatment of Acute Promyelocytic Leukemia

Bee, P.C. and Gan, G.G. and Sangkar, J.V. and Teh, A. and Goh, K.Y. (2004) A Case of T-Cell Acute Lymphoblastic Leukemia after Treatment of Acute Promyelocytic Leukemia. International Journal of Hematology, 79 (4). pp. 358-360. ISSN 0925-5710

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Official URL: http://link.springer.com/article/10.1532/IJH97.A20...

Abstract

We diagnosed T-cell acute lymphoblastic leukemia (T-ALL) with multiple cytogenetic abnormalities in a 17-year-old girl a year after she had received a diagnosis of acute promyelocytic leukemia (APML). After the diagnosis of APML in June 2001, the patient was treated with idarubicin and all-trans-retinoic acid. In September 1999, her younger sister also received a diagnosis of APML and to date has remained well. T-ALL after remission of APML is very rare, and only 1 such case has been reported. Possible causes include therapy-related reasons, genetic susceptibility to leukemia, and environmental exposure.

Item Type: Article
Uncontrolled Keywords: Therapy-related leukemia; T-cell acute lymphoblastic leukemia; Acute promyelocytic leukemia; Familial leukemia
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 14 Jan 2015 00:42
Last Modified: 14 Jan 2015 00:43
URI: http://eprints.um.edu.my/id/eprint/12018

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