Symptomatic anaemia 17 years after double valve replacement.

Wong, M.H.; Chee, K.H.; Azman, W. (2009) Symptomatic anaemia 17 years after double valve replacement. Singapore medical journal, 50 (10). pp. 362-4. ISSN 0037-5675

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A 40-year-old Malay woman presented with increasing lethargy, palpitation and shortness of breath, 17 years after a mitral and aortic valve replacement. A Starr-Edwards prosthetic valve replaced the mitral valve, and a Bjork-Shiley prosthetic valve replaced the aortic valve. Biochemical parameters demonstrated intravascular haemolysis, as evidenced by haemoglobin 7.8 g/dL, reticulocyte count 8.4%, lactate dehydrogenase 2,057 IU/L and low haptoglobulin levels (less than 6 mg/dL). Transoesophageal echocardiography revealed a paravalvular leakage over the mitral valve. The haemoglobin levels remained persistently low despite frequent blood transfusions. She successfully underwent a second mitral valve replacement. Her anaemia resolved subsequently.

Item Type: Article
  1. Wong, M.H.
  2. Chee, K.H.
  3. Azman, W.
Journal or Publication Title: Singapore medical journal
Additional Information: Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.
Uncontrolled Keywords: Adult; Anemia/diagnosis; Anemia/etiology
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Mr. Faizal Hamzah
Date Deposited: 05 May 2011 09:46
Last Modified: 05 May 2011 09:46

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