Enyne- and enediyne-y-lactonefrso m the bark of Meiogyne cylindrocarpa

Awang, Khalijah and Bousseroul, H. and Guéritte, F. and Litaudon, M. (2012) Enyne- and enediyne-y-lactonefrso m the bark of Meiogyne cylindrocarpa. Phytochemistry Letters, 5. pp. 29-32. ISSN 1874-3900

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Abstract

The chemical investigation ofthe EtOAc extract ofthe bark ofMeiogrne qilindrocarpa led to the isolation of two enyne- and five enediynel-lactones, sapranthins A-G (1 -7), of which six were new. They were identified by mass spectrometry,extensive one- and two-dimensional NMR spectroscopya nd through comparison with data reported in the Iiterature.S apranthinsB , C and E (2,3 and 5, respectively showed a weak cytotoxic activity on L1210 with lC50 values comprised between 8.1 and 18.0 µM.

Item Type: Article
Additional Information: Department of chemistry, University of Malaya
Uncontrolled Keywords: Meiogyne cllindrocarpa; Annonaceae; Enyne-y-lactones; Enediyne-y-lactones; Acetylenic lactones; Polyynes.
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Science > Dept of Chemistry
Depositing User: Ms. Suhaila Syakila Alby
Date Deposited: 15 Oct 2014 00:56
Last Modified: 08 Mar 2019 08:36
URI: http://eprints.um.edu.my/id/eprint/10450

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