In vivo genetic stability of Salmonella typhi detected by ribotyping and pulsed field gel electrophoresis

Thong, Kwai Lin and Puthucheary, S.D. and Pang, T. (1995) In vivo genetic stability of Salmonella typhi detected by ribotyping and pulsed field gel electrophoresis. Asia Pacific Journal of Molecular Biology and Biotechnology, 3 (4). pp. 356-361.

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Abstract

Ribotyping, PCR-ribotyping and pulsed-field gel electrophoresis were used to analyze five serial isolates of Salmonella typhi obtained from a single patient with relapsing typhoid fever over a 7-week period. The 5 isolates were genetically identical by all three methods thus suggesting relapsing infection with the same strain and implying in vivo genomic stability of S. typhi even in the presence of selective pressures of antibiotic treatment and host defenses.

Item Type: Article
Uncontrolled Keywords: thongkl@um.edu.my
Subjects: Q Science > QR Microbiology
Divisions: Faculty of Science > Institute of Biological Sciences
Depositing User: Prof. Dr Kwai Lin Thong
Date Deposited: 10 Jun 2014 01:26
Last Modified: 12 Oct 2018 06:27
URI: http://eprints.um.edu.my/id/eprint/10423

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