Outbreak of typhoid fever in non-endemic area: comparison of three molecular typing methods

Gruner, E. and Flepp, M. and Gabathuler, U. and Thong, Kwai Lin and Altwegg, M. (1997) Outbreak of typhoid fever in non-endemic area: comparison of three molecular typing methods. Journal of Microbiological Methods, 28 (1997). pp. 179-185.

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Abstract

An outbreak of typhoid fever in Zurich, Switzerland, which involved seven customers and three employees of a city mall restaurant, was investigated by comparing three molecular typing methods: pulsed-field gel electrophoresis (PFGE), ribosomal RNA gene restriction patterns (ribotyping), and random amplified polymorphic DNA (RAPD). Both PFGE and ribotyping identified two molecular patterns among the outbreak-related isolates which differed in one band: these isolates were considered clonally related and differed clearly from other unrelated S. typhi strains. RAPD could not distinguish among outbreak isolates and control strains.

Item Type: Article
Subjects: Q Science > QR Microbiology
Divisions: Faculty of Science > Institute of Biological Sciences
Depositing User: Prof. Dr Kwai Lin Thong
Date Deposited: 10 Jun 2014 01:22
Last Modified: 12 Oct 2018 06:32
URI: http://eprints.um.edu.my/id/eprint/10420

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