Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis

Kam, Toh Seok and Gan, C.Y. and Low, Y.Y. and Robinson, W.T. and Komiyama, K. (2010) Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis. Phytochemistry, 71. pp. 1365-1370. ISSN 0031-9422, DOI https://doi.org/10.1016/j.phytochem.2010.05.015.

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Abstract

Leucofoline and leuconoline, representing the first members of the aspidospermatan–aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii. The structures of these bisindole alkaloids were established using NMR and MS analysis, and in the case of leuconoline, confirmed by X-ray diffraction analysis. Both alkaloids showed weak cytotoxicity towards human KB cells.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Bisindole alkaloids; Leuconotis; NMR; X-ray; Cytotoxicity.
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Science > Department of Chemistry
Depositing User: Ms. Suhaila Syakila Alby
Date Deposited: 10 Jun 2014 01:41
Last Modified: 22 Mar 2021 03:38
URI: http://eprints.um.edu.my/id/eprint/10406

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