Chuah, C.H. and Tan, H.P. and Ling, S.K. (2011) Characterization of galloylated cyanogenic glucosides and hydrolysabletannins from leaves of Phyllagathis rotundifolia by LC-ESI-MS/MS. Phytochemical Analysis, 22. pp. 516-525. ISSN 0958-0344, DOI https://doi.org/10.1002/pca.1312.
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Abstract
Introduction: Phyllagathis rotundifolia (Jack) Bl. (Melastomataceae) is a creeping herb found in Peninsular Malaysia and Sumatra. Traditionally, a decoction of the leaves is used in the treatment of malaria, fever and stomach ache. Objective:To provide ESI‐MSⁿ data which are applicable for chemical fingerprinting of P. rotundifolia to obviate laborious isolation and purification steps. Methodology:The mass spectral data for the compounds isolated from the leaves of P. rotundifolia were obtained by liquid chromatography–electrospray ionisation tandem mass spectrometry. Results: The MS fragmentation patterns were obtained for galloylated cyanogenic glucosides based on prunasin (prunasin 6′‐O‐gallate 1, prunasin 2′,6′‐di‐O‐gallate 2, prunasin 3′,6′‐di‐O‐gallate 3, prunasin 4′,6′‐di‐O‐gallate 4, prunasin 2′,3′,6′‐tri‐Ogallate 5, prunasin 3′,4′,6′‐tri‐O‐gallate 6 and prunasin 2′,3′,4′,6′‐tetra‐O‐gallate 7), gallotannins (6‐O‐galloyl‐D‐glucose 8, 3,6‐di‐ O‐galloyl‐D‐glucose 9, 1,2,3‐tri‐O‐galloyl‐β‐D‐glucose 10, 1,4,6‐tri‐O‐galloyl‐β‐D‐glucose 11, 3,4,6‐tri‐O‐galloyl‐D‐glucose 12,1,2,3,6‐tetra‐O‐galloyl‐β‐D‐glucose 13 and 1,2,3,4,6‐penta‐O‐galloyl‐β‐D‐glucose 14), ellagitannins [6‐O‐galloyl‐2,3‐O‐(S)‐ hexahydroxy‐diphenoyl‐D‐glucose 15, praecoxin B 16 and pterocarinin C 17], ellagic acid derivatives (3′‐O‐methyl‐3,4‐methylenedioxyellagic acid 4′‐O‐β‐D‐glucopyranoside 18 and 3,3′,4‐tri‐O‐methylellagic acid 4′‐O‐β‐D‐glucopyranoside 19) and gallic acid 20 that were isolated from the leaves of P. rotundifolia. Conclusion: The ESI‐MSⁿ technique facilitates identification of galloylated cyanogenic glucosides, hydrolysable tannins and ellagic acid derivatives that were isolated from the leaves of P. rotundifolia. It yields MSⁿ spectra that are useful for identification of these compounds in complex samples and permit more complete fingerprinting of plant materials.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Additional Information: | Phytochemical Analysis |
| Uncontrolled Keywords: | Phyllagathis rotundifolia; Melastomataceae; galloylated cyanogenic glucosides; hydrolysable tannins; ellagic acid derivative; liquid chromatography–mass spectrometry. |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science > Department of Chemistry |
| Depositing User: | Ms. Suhaila Syakila Alby |
| Date Deposited: | 04 Nov 2014 03:14 |
| Last Modified: | 04 Nov 2014 03:14 |
| URI: | http://eprints.um.edu.my/id/eprint/10326 |
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