Ceftriaxone resistance and genes encoding extended-spectrum ß-lactamase among non-typhoidal salmonella species from a tertiary care hospital in Kuala Lumpur, Malaysia

Karunakaran, R. and Sun, T.T. and Rahim, F.F. and Bee, B.L. and Sam, I.C. and Kahar-Bador, M. and Hassan, H. and Puthucheary, S.D. (2012) Ceftriaxone resistance and genes encoding extended-spectrum ß-lactamase among non-typhoidal salmonella species from a tertiary care hospital in Kuala Lumpur, Malaysia. Japanese Journal of Infectious Diseases, 65. ISSN 1344-6304

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Abstract

The prevalence of ceftriaxone resistance and the associated genes encoding extended-spectrum ß-lactamase (ESBL) was determined in 149 non-duplicate non-typhoidal Salmonella isolated in 2008–2009 from patients in a tertiary care hospital in Kuala Lumpur, Malaysia. The resistance rate to ceftriaxone was 2.7z (2/74) in 2008, 4.0z (3/75) in 2009, and 3.4z (5/149) overall. CTX-M ESBL genes were detected in 2 of the 5 ceftriaxone-resistant isolates. The prevalence of ceftriaxone resistance, although low, is a concern because it limits therapeutic options. Continued surveillance of ceftriaxone resistance is important to monitor its trends

Item Type: Article
Additional Information: Department of Medical Microbiology, Faculty of Medicine, University of Malaya
Uncontrolled Keywords: Resistant; Sensitive; Intermediate; Ceftriaxone; Ciprofloxacin; Chloramphenicol; Tetracycline; Ampicillin; Trimethoprim-Sulfamethoxazole; Nalidixic Acid; Imipenem
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine > School of Medicine
Depositing User: Ms. Jamilah Salleh
Date Deposited: 23 Oct 2014 08:30
Last Modified: 23 Oct 2014 08:30
URI: http://eprints.um.edu.my/id/eprint/10170

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