The triad of erectile dysfunction, testosterone deficiency syndrome and metabolic syndrome: findings from a multi-ethnic Asian men study (The Subang Men’s Health Study)

Tan, Wei Shen and Ng, Chirk Jenn and Khoo, Ee Ming and Low, Wah Yun and Tan, Hui Meng (2011) The triad of erectile dysfunction, testosterone deficiency syndrome and metabolic syndrome: findings from a multi-ethnic Asian men study (The Subang Men’s Health Study). Aging Male, 14 (4). pp. 231-236. ISSN 1368-5538, DOI https://doi.org/10.3109/13685538.2011.597463.

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Official URL: https://doi.org/10.3109/13685538.2011.597463

Abstract

The etiology of erectile dysfunction (ED) is multi-factorial. This paper examines the association between ED, testosterone deficiency syndrome (TDS) and metabolic syndrome (MS) in Malaysian men in an urban setting. One thousand and forty-six men aged >= 40 years from Subang Jaya, Malaysia were randomly selected from an electoral-roll list. The men completed questionnaires that included: socio-demographic data, self-reported medical problems and the International Index of erectile function (IIEF-5). Physical examination and the following biochemical tests were performed: lipid profile, fasting blood glucose (FBG) and total testosterone. The response rate was 62.8 and the mean age of men was 55.8 +/- 8.4 (41-93) years. Ethnic distribution was Chinese, 48.9; Malay, 34.5; Indian, 14.8. The prevalence of moderate. severe ED was 20.0, while 16.1 of men had TDS (< 10.4 nmol/L) and 31.3 of men had MS. Indian and Malay men were significantly more likely to have ED (p = 0.001), TDS (p < 0.001) and MS (p < 0.001) than the Chinese. Multivariate regression analysis showed that elevated blood pressure, elevated FBG, low high-density lipoprotein and heart disease were predictors of ED while all MS components were independently associated with TDS. Malay and Indian men have a higher disease burden compared to Chinese men and were more likely to suffer with ED, TDS and MS. MS components were closely related to TDS and ED.

Item Type: Article
Funders: UNSPECIFIED
Additional Information: Department of Primary Care Medicine, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA
Uncontrolled Keywords: Male sexual dysfunction; testosterone deficiency; metabolic syndrome; Asian men; culture; prevalence; aging male
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms Haslinda Lahuddin
Date Deposited: 21 Oct 2014 04:17
Last Modified: 18 Nov 2019 07:49
URI: http://eprints.um.edu.my/id/eprint/10113

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